Jeri Evans Nutrition www.jerievansnutrition.com An infecting organism, or pathogen, interferes with your normal functioning. Your body's response to infection is inflammation. Parasites reduce your fitness in many ways. Parasitic diseases account for a large proportion of human sicknesses. Candida albicans is a fungus (a form of yeast), which causes oral and genital infections in humans.
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Tuesday, December 20, 2011
Saturday, December 17, 2011
Antidepressant regulation of endpoints relevant to the hypothalamic-pituitary-adrenal axis: Implications for predicting treatment response in depression.
!±8± Antidepressant regulation of endpoints relevant to the hypothalamic-pituitary-adrenal axis: Implications for predicting treatment response in depression.
Elevated hypothalamic pituitary adrenal (HPA) axis activity in depression is proposed to result from impaired HPA feedback and may be a biological marker for the disease. Antidepressant treatment has been suggested to compensate for impaired feedback by increasing brain glucocorticoid (GR) and mineralocorticoid receptors (MR) and thus inhibiting HPA activity. Although elevated HPA activity is associated with melancholic depression, other forms of depression such as atypical depression have been associated with decreased HPA activity and enhanced HPA feedback. These different forms of depression have also shown a differential responsiveness to antidepressant treatment, with melancholic depression being successfully treated with tricyclic antidepressants (TCA) and atypical depressives showing a preferential responsiveness to monoamine oxidase inhibitors (MAOI). Because successful antidepressant treatment has been correlated with normalization of HPA activity, and previous studies in our lab have shown opposing effects of TCA and MAOI on measures of HPA activity we hypothesized that chronic TCA treatment would increase and MAOI treatment would decrease corticosteroid receptor expression in glucocorticoid feedback-related brain regions. We further hypothesized that in order for antidepressants to alter glucocorticoid feedback sensitivity without exacerbating effects of glucocorticoids on mood, antidepressant-induced changes in GR and MR expression must be brain region-specific. In support of our hypothesis, we found brain region-specific, often opposing, effects of the prototypic TCA imipramine and the prototypic MAOI phenelzine on GR and MR gene expression. Currently however, selective serotonin reuptake inhibitors (SSRIs) are more often prescribed than TCA or MAOI for a wide variety of depression subtypes. We therefore hypothesized that chronic SSRI treatment would have effects on GR and MR gene expression that are shared with both TCA and MAOI. In support of this hypothesis, chronic treatment with the prototypic SSRI, fluoxetine had effects that resembled those of both TCA and MAOI treatment. Further antidepressant-induced changes in glucocorticoid-regulated endpoints were consistent with antidepressant effects on corticosteroid receptor expression, indicating that antidepressant effects on GR and MR are likely to be physiologically relevant. By, defining antidepressant-specific effects on HPA relevant-endpoints, these findings may aid in the use of the HPA testing to improve the prediction and detection of antidepressant response in depression.
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Saturday, December 10, 2011
Dr. Michael Borkin, NMD How You Overcome Doubts & Fears
Toget your health questions answered visit our blog www.healthydoctors.com . Type in your search words in the search box. Dr. Borkin and Dr. Robert Rowen, MD understand when to use allopathic, conventional, alternative, complimentary and oxidative medicine to help their patients heal and experience optimal health. Dr. Michael Borkin, NMD is a pioneer in hormone and electrolyte research. He specializes in hormone and electrolyte testing and balancing. For more information contact him at: 888-285-9098 or by email: doctorborkin@gmail.com. His evaluation of hormones levels in patients provides an in-depth snap shot of the health level and disease processes. These tests and the unique balancing programs created by the trained doctors and lab technicians are incredibly valuable for individuals who have used anabolic steroids, HGH (human growth hormone), insulin, testosterone and progesterone without understanding the importance of exact supplementation in response to test results. Gross dosing without testing has caused many people to be biochemically and hormonally out of balance. Dr. Michael Borkin is also one of the creators of the science of bio-identical hormones and transdermal (through the skin) creams. Unique creams are created for each patient to restore hormonal homeostasis. The creams are made up of hormones, hormone precursors, nutrients, homeopathics, herbs and electrolytes. Specific electrolyte and nutrient rich supplements help balance each patient's bio ...
Tuesday, December 6, 2011
Innate Response Formulas Adrenal Response- Complete Care - 90 Tablets
!±8± Innate Response Formulas Adrenal Response- Complete Care - 90 Tablets
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| Price : $74.05 | Post Date : Dec 06, 2011 23:12:48Usually ships in 1-2 business days
Adrenal Responseâ"¢- Complete Care is a meticulously researched adaptogenic formula that uses clinically proven nutrients, herbs and whole foods to assist the adrenal glandâ?TMs natural response.
Tuesday, November 29, 2011
Rundown - Chronically Tired - Listless - You May Have Adrenal Fatigue
Peggy was a highly-driven and successful career woman with boundless energy who had worked long days for several years. Healthy and vibrant, she seemed indestructible. Then one of her children got seriously sick, and as she helped nurse him back to health, her own health began to suffer. Long after her son had recovered she still felt weak and listless throughout the day, and eventually she began to have problems getting out of bed in the morning. She went to the doctor, but he could find nothing physically wrong with her. Finally a nurse-friend suggested that she might have adrenal fatigue.
What is adrenal fatigue? Although it can be caused by several different things, it usually involves stress and the body's response to stress. The response to stress comes into play when the brain senses an emergency. It goes into what is referred to as the "fight or flight" mode. Within a fraction of a second, a region of the brain called the hypothalamus sends a signal to the adrenal glands. (They are glands that sit on the top of the kidneys.) When they receive the signal they excrete adrenaline that rushes to the heart and other parts of the body. The heart responds by beating faster, which in turn, sends extra blood to the muscles and organs. At the same time the respiratory rate increases and the lungs rush extra oxygen to the brain. The brain then releases endorphins which help the body function more efficiently, and finally the adrenaline helps increase the body's energy by releasing glucose from its glycogen stores.
The Adrenaline surge is just the first part of the stress response; once it is underway, the adrenal glands also secrete cortisol. It surges through the body performing many important functions: it replaces the energy that the adrenaline rush has depleted, it is used by the immune system to put it on alert, and it acts as a check on the overall response, and when it is complete, it signals the brain to stop it.
It's easy to see from the above that the adrenal glands play a vital role in our body. They help us respond to stressful situations and they protect our body. The problem is that our lives are now so full of stress that stressful events frequently come one after the other, with several occurring in a day. And each time they occur the adrenal glands have to respond, and if they are forced to respond too frequently they start to run down and wear out. When this happens they are soon operating well below their optimum; this is what we refer to as adrenal fatigue. It's important to point out, however, that while stressful events are a major factor in adrenal fatigue, many other things also contribute to it. Some of them are: poor diet, lack of exercise, lack of sleep, overuse of stimulants such as coffee, and illness.
The major symptoms of adrenal fatigue are: chronic fatigue, trouble getting out of bed in the morning, problems sleeping, low energy, depression, weight gain, lack of endurance, problems handling stress, and a craving for salt. It's important to catch the condition at this stage; if it is ignored, the adrenal glands will eventually stop working, a condition referred to as Addison's disease. Addison's disease causes such things as suppression of the immune system, muscle and bone loss, hormonal imbalance, and it can be fatal.
One of the major difficulties with adrenal fatigue is that it is not universally recognized by the medical profession, and many physicians are not familiar with it. And although it is important to talk to your doctor about it, drugs are usually not needed to overcome it. The major thing that is needed is a lifestyle change. Stress is the main thing that brings it on, so the first thing you have to do is get rid of any stress in your life. In addition, however, several other things are needed. The major ones are:
1. Take more breaks and concentrate on relaxing.
2. Regular meals and better nutrition are important. Concentrate on getting enough vegetable, whole grains, nuts, and fish (for omega-3). Also, avoid hydrogenated fat, coffee, simple carbohydrates, and junk food.
3. Exercise, but don't overdo it. Aerobic exercise is particularly important, but you should couple it with some weight lifting.
4. Make sure you get to bed early and get enough sleep.
5. Several supplements are also helpful. some of the best are:
Vitamin C, Vitamin E, Vitamin B-6, B-complex, Niacin, and minerals, Magnesium, zinc, selenium and chromium. Finally, licorice and ginseng are also helpful.
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